| Key Ingredients Found in Isotonix™ Advanced B-Complex: Cyanocobalamin (Vitamin B12): 120µg
Vitamin B12 (cyanocobalamin) is a bacterial product naturally found in animal products, especially organ meats such as liver, with small amounts derived from peanuts and fermented soy products, such as miso and tempeh. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. It supports the maintenance of cells, especially those of the nervous system, bone marrow and intestinal tract. Vitamin B12 is important in homocysteine metabolism (homocysteine is an amino acid that is formed within the body). Normal homocysteine levels are important for maintaining cardiovascular health. Deficiencies of the vitamins folic acid, pyridoxine (B6) or cobalamin (B12) can result in elevated levels of homocysteine). Folic Acid (Folate): 500 µg
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans, peas and Brewer's yeast are the best sources. Folic acid plays a key role by boosting the benefits of vitamin B12. These two B vitamins work synergistically in maintaining normal red blood cells. Folic acid assists in the normal utilisation of amino acids and proteins, as well as supporting the construction of the material for DNA and RNA synthesis, which is necessary for all bodily functions. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system. Riboflavin-5-Phosphate (Vitamin B2): 2.25 mg
Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a coenzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and helps regulate thyroid activity (a healthy thyroid is essential in maintaining a healthy weight, among other things). Vitamin B2 plays a crucial role in turning food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 also aids in the breakdown of fats. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily. Pyridoxine Hydrochloride (Vitamin B6): 5 mg
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. B6 is a co-factor required for protein and amino acid metabolism and helps maintain proper fluid balance. It also assists in the maintenance of healthy red and white blood cells which keeps our body healthy. Vitamin B6 is required for haemoglobin synthesis (haemoglobin is the protein portion of red blood cells which carries oxygen throughout the body). Because vitamin B6 is involved in the synthesis of neurotransmitters in the brain and nerve cells, it has been recommended as a nutrient to enhance mental function, specifically mood. Athletic supplements often include vitamin B6 because it promotes the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes optimal cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B-vitamins for best results. Magnesium (Carbonate): 40 mg
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green, leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium. Magnesium is a component of the mineralised part of bone and promotes the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenalin and insulin. It also supports the transportation of calcium inside the cell for utilisation. Magnesium plays a key role in the functioning of muscle and nervous tissue, and the synthesis of all proteins, nucleic acids, nucleotides, fats and carbohydrates. Magnesium helps slow the ageing process by combating oxidative stress. Magnesium is required for releasing energy from food during metabolism, regulation of body temperature, proper nerve function and helping the body handle stress. Importantly, magnesium also promotes is also required by the body to build healthy bones, teeth and normal muscle development. It works together with calcium and vitamin D to help keep bones strong. Magnesium, when combined with calcium, helps support the heart muscle in maintaining a regular heartbeat and promoting normal blood pressure. Potassium (Bicarbonate): 94 mg
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, potassium promotes the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids and the maintenance of normal blood pressure. In 1928, it was first suggested that high potassium intake could help maintain cardiovascular health. Potassium promotes normal muscle relaxation and insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat.Potassium is important in releasing energy from protein, fat and carbohydrates during metabolism. Potassium helps regulate water balance, aids in recovery from exercise and helps with the elimination of wastes. Sodium and potassium are two of the most important ions in maintaining the homeostatic equilibrium of the body fluids. Thiamine Hydrochloride (Vitamin B1): 2 mg
Thiamine promotes normal carbohydrate metabolism and nerve function. Thiamine is required for a healthy nervous system, and supports the production of certain neurotransmitters which have an important role in muscle function. It supports the digestive process, increases energy and helps promote mental clarity. Calcium Pantothenate (Vitamin B5): 22 mg
Pantothenic acid (Vitamin B5) promotes proper neurotransmitter activity in the brain. Pantothenic acid is also known as the anti-stress vitamin because it detoxifies brain tissue, helps relieve physical and emotional stress, and promotes the secretion of hormones essential for optimal health. Nicotinamide (Vitamin B3): 20 mg
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. Niacin supports the proper functioning of the digestive system, skin and nerves. It is also important for the conversion of food to energy. Niacin is found in dairy products, poultry, fish, lean meats, nuts, eggs, legumes, and enriched breads and cereals. Biotin (Vitamin B7): 300 μg
Biotin can be found in food sources such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer's yeast. Biotin promotes healthy cell growth, the production of fatty acids, metabolism of fats and amino acids. It supports the citric acid cycle, which is the process in which energy is generated during exercise. Biotin is also helpful in maintaining steady blood sugar levels. Biotin is often recommended for strengthening hair and nails.
These 10 ingredients combined with the superior delivery of Isotonix create a powerhouse B vitamin product superior to the rest on the market. Isotonix Advanced B-Complex delivers all of the B vitamins along with select minerals and electrolytes to help increase energy, decrease stress, improve mood, and much more. The isotonic delivery system ensures maximum absorption and utilisation by the body for optimal results.
Back to Top |
| Scientific Studies Which Support Isotonix™ Advanced B-Complex: - Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
- Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
- Bhagavan, H. N., et al. The effect of pyridoxine hydrochloride on blood serotonin and pyridoxal phosphate contents in hyperactive children. Pediatrics. 55(3):437-441, 1975.
- Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
- Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
- Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
- combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
- Coppen, A., et al. Plasma folate and affective morbidity during long-term lithium therapy. Br J Psychiatry. 141:87-89, 1982.
- Cummings, P. M., et al. Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 36:758-765, 2000.
- Dharmarajan, T. S., et al. Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics. 58(3):30-34, 2003.
- Doshi, S. N., et al. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation. 105(1):22-26, 2002.
- Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
- Friso, S., et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr. 79(6):992-998, 2004.
- Grant, J. E., et al. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 96(4):383-386, 1996.
- Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
- Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 92(4):183-185, 1999.
- Heseker, H., et al. Psychological disorders as early symptoms of a mild-to-moderate vitamin deficiency. Ann N Y Acad Sci. 669:352-357, 1992.
- Jacobson, W., et al. Serum folate and chronic fatigue syndrome. Neurology. 43:2645-2647, 1993.
- Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4 (4):249-265, 1999.
- Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise. 17(Supplement):287, 1985.
- Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
- Quadri, P., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr. 80(1):114-122, 2004.
- Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
- Van den Berg M., et al. Combined vitamin B-6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia. Journal Vascular Surgery. 20(6):933-940, 1994.
- van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
- Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
- Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
- Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review. 5(2):93-108, 2000.
- Woo, K. S., et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. American Journal of Medicine. 112(7):535-539, 2002.
Back to Top |
| Frequently Asked Questions About Isotonix™ Advanced B-Complex: What is the source of the vitamin B12 in our Isotonix Advanced B-Complex?
Vitamin B-12 comes from bacteria; it is not synthesised by plants or animals. We get it by taking supplements or by eating eggs or meats. Vegetarians are recommended to take a B vitamin dietary supplement. Why are B-vitamins so important in the aging process?
The ability to absorb B-vitamins naturally decreases with age, and various indicators of reduced cognitive performance are associated with reduced B-vitamin levels. The elderly often suffer from a reduction in sense of taste and thus appetite. They also frequently use acid reducing medicines that predispose them to B12 deficiency. According to Robert M. Russell of the U.S. RDA's Human Nutrition Center on Aging at Tufts University, vitamin B12 is probably the single most important nutrient adversely affected by aging. Vitamin B12 is at once an incredibly difficult nutrient to assimilate and digest as well as one of the most important vitamins for the support of a broad range of bodily functions including optimal functioning of the nervous system, normal DNA and RNA synthesis, optimal energy production and healthy blood integrity. Is it toxic to take too much vitamin B12?
Studies have found no confirmed reports of toxic side effects from heightened servings of vitamin B12. However, you should only take Isotonix Advanced B-Complex as directed on the bottle. Are there any warnings or contraindications for Isotonix Advanced B-Complex?
Isotonix Advanced B-Complex is a vegetarian product and contains no wheat, gluten, soy, yeast, artificial flavour, starch, salt, preservatives or milk. If you are currently using any prescription drugs, have ongoing medical condition or if you are pregnant or breastfeeding, you should consult your healthcare provider before using this product.
Back to Top |
